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11aR)-7-{[(2R
MGCD0103 improves pulmonary artery acceleration time and reduced systolic notching of the pulmonary artery flow envelope
Baohuoside I suppresses invasion of cervical and breast cancer cells through the downregulation of CXCR4 chemokine receptor expression
9 μg·h/mL) in rats as compared to GW7604 (AUC = 3
Bortezomib entane 11aR)-7-{[(2RHigh affinity proteasome inhibitor (Ki = 0. 6 nM). Inhibits growth of multiple myeloma (MM) cell lines (IC50 values in <50 nM range); induces apoptosis in MM cell lines and MM patient derived cells, including p53 mutant cell lines. Decreases adherence of MM cells lines to bone marrow stromal cells (BMSCs). Acts synergistically with dexamethasone (Cat. No. 1126). Also cytotoxic in MCF 7 breast cancer cell line (IC50 = 50 nM). Product information CAS
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